[{"data":1,"prerenderedAt":40},["ShallowReactive",2],{"pub-archive-china-acta-universitatis-medicinalis-anhui":3},[4,21,31],{"id":5,"timeStamp":6,"permaLink":7,"coverFilename":8,"aspectRatio":9,"publicationDate":10,"hasStory":11,"storyTitle":12,"storyLinkPage":13,"storyLinkKey":14,"storyDescription":15,"countrySlug":16,"countryName":17,"publicationName":18,"publicationSlug":19,"status":20},3679597,"2026-10-03 02:27:04","https://www.pressreader.com/china/acta-universitatis-medicinalis-anhui/20260923","2026/09/23/china-acta-universitatis-medicinalis-anhui",0.7315270935960592,"2026-09-23 00:00:00",1,"Effects of MAGED4 overexpression on proliferation，migration，and adhesion of hepatocellular carcinoma",2,"283459263273245","摘要 目的 探究黑色素瘤相关抗原D4（MAGED4）对肝细胞癌（HCC）恶性生物学行为的影响，为评估其作为HCC潜在治疗靶点提供实验依据。方法 利用Linkedomics数据库筛选HCC中与MAGED4表达呈正相关的基因，并进行GO功能与KEGG通路富集分析。选取内源性MAGED4低表达的SMMC-7721、HUH7细胞，并以正常肝细胞LO2作为对照，通过慢病毒感染构建稳定过表达细胞株（MAGED4过表达组），并采用逆转录-聚合酶链式反应（RT-PCR）与Western...","china","China","Acta Universitatis Medicinalis Anhui","acta-universitatis-medicinalis-anhui","alive",{"id":22,"timeStamp":23,"permaLink":24,"coverFilename":25,"aspectRatio":9,"publicationDate":26,"hasStory":11,"storyTitle":27,"storyLinkPage":28,"storyLinkKey":29,"storyDescription":30,"countrySlug":16,"countryName":17,"publicationName":18,"publicationSlug":19,"status":20},3668859,"2026-09-25 21:42:04","https://www.pressreader.com/china/acta-universitatis-medicinalis-anhui/20260823","2026/08/23/china-acta-universitatis-medicinalis-anhui","2026-08-23 00:00:00","SAC1介导的巨噬细胞NLRP3炎症小体激活在MASH炎症进展中的作用",5,"281509348104241","孙志阳，曹新旺（安徽医科大学生命科学学院细胞生物学系，合肥摘要 目的 探究SAC1样磷脂酰肌醇磷酸磷酸酶（SAC1）调控巨噬细胞核苷酸结合寡聚化结构域样受体蛋白3（NLRP3）炎症小体激活的分子机制及其在代谢功能障碍相关脂肪性肝炎（ MASH ）病理进程中的作用。方法 利用单细胞RNA测序（scrna-seq）分析对照组和MASH小鼠肝脏巨噬细胞亚群中SACM1L的表达水平差异。分离并培养对照组和高脂饮食组小鼠骨髓来源巨噬细胞（BMDMS），通过RT-QPCR及 Western...",{"id":32,"timeStamp":33,"permaLink":34,"coverFilename":35,"aspectRatio":9,"publicationDate":36,"hasStory":11,"storyTitle":37,"storyLinkPage":38,"storyLinkKey":39,"storyDescription":37,"countrySlug":16,"countryName":17,"publicationName":18,"publicationSlug":19,"status":20},3651865,"2026-09-14 17:17:05","https://www.pressreader.com/china/acta-universitatis-medicinalis-anhui/20260723","2026/07/23/china-acta-universitatis-medicinalis-anhui","2026-07-23 00:00:00","破壁灵芝孢子粉通过调控Nrf2通路保护DEN/CCL4诱导的小鼠肝癌模型⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅⋅",3,"283162910481847",1792930805789]